Changes in the levels of a genetic “messenger” are linked with the development of alcohol use disorders, according to researchers from the University of California, San Francisco. The investigators found that when mice ingested excessive amounts of alcohol for a long time, levels of the protein BDNF dropped in the area of the brain that is important for decision-making. The decline of BDNF in that area, the medial prefrontal cortex, corresponded with an increase in the level of a genetic messenger, or microRNA, called miR-30a-5p.
Follow this link:
Genetic "Messenger" May Affect Alcohol Disorders